Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4)

Philomena Alapatt, Fangjian Guo, Susan M. Komanetsky, +7

Journal of Biological Chemistry

Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability

Leena P. Bharath, Robert A. Mueller, Youyou Li, +9

Canadian Journal of Physiology and Pharmacology

MitophagyEndothelial CellsIncreased AutophagyLung InflammationLipid Peroxidation +23

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Jinjin Cai, Karla Maria Pereira Pires, Maroua Ferhat, +8

Cell Reports

MitophagyCell DeathNrf2 SignalingFatty Liver DiseaseInsulin Signaling +19

The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets

Kimberley El, Jonathan D. Douros, Francis S. Willard, +14

Nature Metabolism

Endothelial Cell Autophagy Maintains Shear Stress–Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase

Leena P. Bharath, Jae Min Cho, Seul-Ki Park, +13

Arteriosclerosis Thrombosis and Vascular Biology

Intestinal, but not hepatic, ChREBP is required for fructose tolerance

Mi-Sung Kim, Inna Astapova, Sarah N. Flier, +7

JCI Insight

Hepatocytes Are the Principal Source of Circulating RBP4 in Mice

S.J. Thompson, Ashot Sargsyan, Seung‐Ah Lee, +7

Diabetes

Blood CellAdipocyte Rbp4Cellular PhysiologyInsulin SignalingOxidative Stress +25

Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor

Ashot Sargsyan, Jinjin Cai, Luis Fandino, +5

Scientific Reports

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

Ashot Sargsyan, Ludivine Doridot, Sarah Anissa Hannou, +12

JCI Insight

ImmunologyMetabolic RemodelingHuman HgfacChrebp-regulated HepatokineSystemic Fuel Homeostasis +22

The intestine is a major contributor to circulating succinate in mice

Wenxin Tong, Sarah Anissa Hannou, You Wang, +10

The FASEB Journal

NutritionDysbiosisGastroenterologyDigestive TractOxidative Stress +20