An adenosine nucleoside inhibitor of dengue virus

Zheng Yin, Yen‐Liang Chen, Wouter Schul, +30

Proceedings of the National Academy of Sciences

Dengue VirusMolecular VirologyMedicineImmunologyAntiviral Therapy +7

Cholesterol biosynthesis modulation regulates dengue viral replication

Christopher Rothwell, Aude LeBreton, Chuan Young Ng, +6

Virology

Viral ReplicationBiochemistryPathogenesisVirologyCholesterol Biosynthesis Modulation +2

Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8+ T cells

Joanne Y. H. Lim, Scott A. Gerber, Shawn P. Murphy, +1

Cancer Immunology Immunotherapy

Effector FunctionImmunologyImmunologic MechanismAutoimmunityT Cell Immunity +6

ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance

Su Chul Jang, Kyriakos D. Economides, Raymond J. Moniz, +20

Communications Biology

Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel

Pornwaratt Niyomrattanakit, Yen‐Liang Chen, Hongping Dong, +10

Journal of Virology

Viral ReplicationDengue VirusMolecular BiologyRna TunnelAntiviral Drug +16

Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes

Zhihua Kou, Joanne Y. H. Lim, Martina Beltramello, +9

Virology

Autoimmune DiseaseHumoral ResponseViral PathogenesisImmunologyAntiviral Response +6

<i>N</i>-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase

Zheng Yin, Yen‐Liang Chen, Ravinder Reddy Kondreddi, +17

Journal of Medicinal Chemistry

Bioorganic ChemistryViral Polymerase StructureAllosteric InhibitorsAntiviral DrugChemical Biology +16

Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors

Scott A. Gerber, Joanne Y. H. Lim, Kelli A. Connolly, +5

International Journal of Cancer

ImmunologyImmunoeditingImmune SystemImmunotherapyTumor Biology +14

Local expression of interleukin‐2 by B16 melanoma cells results in decreased tumour growth and long‐term tumour dormancy

Scott A. Gerber, Elizabeth W. Sorensen, Abigail L. Sedlacek, +4

Immunology

Radiation therapy combined with<i>Listeria monocytogenes</i>-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model

Joanne Y. H. Lim, Dirk G. Brockstedt, Edith M. Lord, +1

OncoImmunology