Isabelle Rooney

Cobimetinib combined with vemurafenib in advanced BRAFV600-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial

Paolo A. Ascierto, Grant A. McArthur, Brigitte Dréno et al. · The Lancet Oncology · 2016 · 986 citations

Medicine, Advanced Brafv600-mutant Melanoma, Melanoma +7

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis

Jennifer L. McQuade, Carrie R. Daniel, Kenneth R. Hess et al. · The Lancet Oncology · 2018 · 647 citations · Full text

Oncology, Body Composition, Cancer Management +8

Impact of the ΔF508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure

H.A. Lewis, Xun Zhao, Chi Chiu Wang et al. · Journal of Biological Chemistry · 2004 · 272 citations · Full text

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.

Mohammed Saifuddin, Charles J. Parker, Mark E. Peeples et al. · The Journal of Experimental Medicine · 1995 · 246 citations · Full text

Immunology, Immunotherapy, Human Retrovirus +16

The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

Isabelle Rooney, Kris D. Butrovich, Alison A. Glass et al. · Journal of Biological Chemistry · 2000 · 225 citations · Full text

Immunotoxicology, Apoptosis, Immunology +22