Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin

Sai Ma, Bing Zhang, Lindsay M. LaFave, +12

Cell

Chromatin Potential IdentifiedChromatinChromatin RemodelingSingle Cell SequencingMedicine +11

Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics

Leif S. Ludwig, Caleb A. Lareau, Jacob C. Ulirsch, +16

Cell

Genetic AnalysisSingle Cell SequencingMedicineGeneticsMitochondrial Mutations +5

A large peptidome dataset improves HLA class I epitope prediction across most of the human population

Siranush Sarkizova, Susan Klaeger, Phuong M. Le, +22

Nature Biotechnology

HlaHistocompatibilityImmunogeneticsAutoimmune DiseaseHuman Leukocyte Antigen +12

Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Norio Chihara, Asaf Madi, Takaaki Kondo, +18

Nature

Transcriptional RegulationSystems BiologySignal TransductionT CellsCo-inhibitory Gene Module +10

CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

Rebecca C. Larson, Michael C. Kann, Stefanie R. Bailey, +17

Nature

Liquid TumoursCancer ImmunosurveillanceImmunologyTumor ImmunityCell Death +9

Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer

Tamara Ouspenskaia, Travis Law, Karl R. Clauser, +26

Nature Biotechnology

Cancer ImmunosurveillanceImmunologyImmunoeditingAntigen ProcessingAutoimmunity +5

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

Lindsay M. LaFave, Vinay K. Kartha, Sai Ma, +15

Cancer Cell

Tumor HeterogeneityMedicineCancer GenomicsCancer BiologyCell Biology +8

Chromatin potential identified by shared single cell profiling of RNA and chromatin

Sai Ma, Bing Zhang, Lindsay M. LaFave, +10

GeneticsLineage CommitmentGene Regulatory NetworkGene Expression ProfilingEpigenetics +20

Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma

Sidharth V. Puram, Michael Mints, Ananya Pal, +24

Nature Genetics

Hpv-related Oropharyngeal CarcinomaViral HeterogeneityPathologyVirologyHead And Neck Squamous Cell Carcinoma +8

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

Tamara Ouspenskaia, Travis Law, Karl R. Clauser, +24

ImmunologyMore Nuorf PeptidesPathologyImmunoeditingAntigen Processing +20