The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Susanne Krasemann, Charlotte Madore, Ron Cialic, +35

Immunity

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineCell DeathNeurochemical Biomarkers +10

Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Sema Kurtuluş, Asaf Madi, Giulia Escobar, +10

Immunity

Tumor ImmunologyCancer ImmunosurveillanceImmune RegulationTumor ImmunityImmunodominance +9

Induction and transcriptional regulation of the co-inhibitory gene module in T cells

Norio Chihara, Asaf Madi, Takaaki Kondo, +18

Nature

Transcriptional RegulationSystems BiologySignal TransductionT CellsCo-inhibitory Gene Module +10

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

Chao Wang, Nir Yosef, Jellert T. Gaublomme, +19

Cell

Molecular ImmunologyImmunologyAutoimmunityCd4 T Cell ResponsesCellular Immune Response +4

Dominating Clasp of the Financial Sector Revealed by Partial Correlation Analysis of the Stock Market

Dror Y. Kenett, Michele Tumminello, Asaf Madi, +3

PLoS ONE

Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

Nandini Acharya, Asaf Madi, Huiyuan Zhang, +17

Immunity

Cancer ImmunosurveillanceLymphocyte DevelopmentT-regulatory CellImmunologyCell Biology +5

Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage

Alessio D. Nahmad, Eli Reuveni, Ella Goldschmidt, +9

Nature Biotechnology

Immune Cell DevelopmentGeneticsImmunologyFrequent AneuploidyCell Development +6

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

Pushpa Jayaraman, Miye K. Jacques, Chen Zhu, +6

PLoS Pathogens

T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity

Asaf Madi, Eric Shifrut, Shlomit Reich-Zeliger, +5

Genome Research

Mhc-diverse Cdr3 SequencesSelf-related ImmunityAdaptive Immune SystemGeneticsT-regulatory Cell +23

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

Asaf Madi, Asaf Poran, Eric Shifrut, +10

eLife

Similarity NetworksAdaptive Immune SystemTcr RepertoiresT-regulatory CellImmunology +25