A model for chromatin opening: stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin.

Chromosomal Subunits in Active Genes Have an Altered Conformation

Harold Weintraub, Mark Groudine · Science · 1976 · 1.8K citations

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

Fritz Thoma, T. Köller, A. Klug · The Journal of Cell Biology · 1979 · 1.5K citations · Full text

Nuclear Structure, Epigenetic Change, Molecular Biology +23

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

Jovan Mirkovitch, Marc-Édouard Mirault, Ulrich K. Laemmli · Cell · 1984 · 1.1K citations

Chromatin, Nuclear Structure, Chromatin Structure +13

DNA bending at adenine · thymine tracts

Hyeon‐Sook Koo, Hen‐Ming Wu, Donald M. Crothers · Nature · 1986 · 1K citations

Chromatin, Dna Nanotechnology, Dna +9

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

Peter N. Cockerill, William T. Garrard · Cell · 1986 · 900 citations

Chromatin, Immunogenetics, Kappa Immunoglobulin Gene +13