In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine

Human Malaria Parasites in Continuous Culture

William Trager, James B. Jensen · Science · 1976 · 8K citations

Life Sciences, Biology, Infectious Diseases +15

Parasite Lactate Dehydrogenase as an Assay for Plasmodium falciparum Drug Sensitivity

Michael T. Makler, Judith Ries, Jeffery A. Williams et al. · American Journal of Tropical Medicine and Hygiene · 1993 · 744 citations

Life Sciences, Biochemistry, Pharmacology +17

Reversal of Chloroquine Resistance in <i>Plasmodium falciparum</i> by Verapamil

Samuel K. Martin, Ayo Oduola, Wilbur K. Milhous · Science · 1987 · 573 citations

Medicine, Infectious Diseases, Pharmacology +17

Efflux of Chloroquine from <i>Plasmodium falciparum</i> : Mechanism of Chloroquine Resistance

Donald J. Krogstad, Ilya Y. Gluzman, Dennis E. Kyle et al. · Science · 1987 · 523 citations

Medicine, Pharmacokinetics, Pharmacology +17

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 311 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10