Timothy J. Egan

Quinoline anti‐malarial drugs inhibit spontaneous formation of β‐haematin (malaria pigment)

Timothy J. Egan, David Ross, Paul A. Adams · FEBS Letters · 1994 · 358 citations · Full text

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 310 citations

Fate of haem iron in the malaria parasite Plasmodium falciparum

Timothy J. Egan, Jill M. Combrinck, J. Egan et al. · Biochemical Journal · 2002 · 284 citations · Full text

Structure−Activity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position

Catherine H. Kaschula, Timothy J. Egan, Roger Hunter et al. · Journal of Medicinal Chemistry · 2002 · 235 citations

A colorimetric high-throughput β-hematin inhibition screening assay for use in the search for antimalarial compounds

Kanyile K. Ncokazi, Timothy J. Egan · Analytical Biochemistry · 2004 · 215 citations

Medicinal Chemistry, Bioassay-guided Isolation, Antiparasitic Agent +12