Timothy J. Egan

Quinoline anti‐malarial drugs inhibit spontaneous formation of β‐haematin (malaria pigment)

Timothy J. Egan, David Ross, Paul A. Adams · FEBS Letters · 1994 · 374 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 311 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Fate of haem iron in the malaria parasite Plasmodium falciparum

Timothy J. Egan, Jill M. Combrinck, J. Egan et al. · Biochemical Journal · 2002 · 287 citations · Full text

Life Sciences, Biochemistry, Chemistry +11

Structure−Activity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position

Catherine H. Kaschula, Timothy J. Egan, Roger Hunter et al. · Journal of Medicinal Chemistry · 2002 · 270 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

A colorimetric high-throughput β-hematin inhibition screening assay for use in the search for antimalarial compounds

Kanyile K. Ncokazi, Timothy J. Egan · Analytical Biochemistry · 2004 · 216 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12