Enantiospecific Synthesis and in vitro Activity of Selective Inhibitors of Rat Brain Kynureninase and Kynurenine-3-Hydroxylase

Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia

Kuniaki Saito, Thaddeus S. Nowak, Sanford P. Markey et al. · Journal of Neurochemistry · 1993 · 166 citations

Delayed Increases, Social Sciences, Kynurenine Pathway Metabolism +18

Practical enantioselective synthesis of a homotyrosine derivative and (R,R)-4-propyl-9-hydroxynaphthoxazine, a potent dopamine agonist

David G. Melillo, Robert D. Larsen, David J. Mathre et al. · The Journal of Organic Chemistry · 1987 · 76 citations

Molecular Pharmacology, Biochemistry, Donut Icon +15

A short enantiospecific synthesis of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN)

J. Eric Nordlander, Mark J. Payne, F. George Njoroge et al. · The Journal of Organic Chemistry · 1985 · 60 citations

Short Enantiospecific Synthesis, Molecular Sciences, Bioorganic Chemistry +14

Friedel-Crafts synthesis of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, a key intermediate in the preparation of the antidepressant sertraline

George J. Quallich, Michael T. Williams, Robert C. Friedmann · The Journal of Organic Chemistry · 1990 · 32 citations

Key Intermediate, Altmetric Attention Score, Organic Chemistry +19

Stereospecific synthesis of the enantiomers of nicotinylalanine, a neuroprotecting agent

Roberto Pellicciari, Miguel Angel Gallo‐Mezo, Benedetto Natalini et al. · Tetrahedron Letters · 1992 · 16 citations

Biochemistry, Medicine, Neuroprotecting Agent +8