Concepedia

A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH‐binding activity by abolishing receptor homodimerization.

Philippe Duquesnoy, Marie‐Laure Sobrier, Bénédicte Duriez, Florence Dastot, C R Buchanan, Martin O. Savage, Michael A. Preece, Constantin T. Craescu, Y. Blouquit, Michel Goossens

The EMBO Journal · 1994 · 156 citations · 42 references

Open access

References

42

The protein data bank: A computer-based archival file for macromolecular structures

F. C. Bernstein, Thomas F. Koetzle, G. J. B. Williams et al. · Journal of Molecular Biology · 1977 · 8.6K citations

Life Sciences, Biochemistry, Bioinformatics +14

A general method of<i>in vitro</i>preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

Russell Higuchi, Barbara Krummel, Randall K. Saiki · Nucleic Acids Research · 1988 · 2.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

Abraham M. de Vos, Mark Ultsch, Anthony A. Kossiakoff · Science · 1992 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +17

Structural design and molecular evolution of a cytokine receptor superfamily.

J. Fernando Bazán · Proceedings of the National Academy of Sciences · 1990 · 2.1K citations

Life Sciences, Immunology, Molecular Biology +17

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

Ulf Gyllensten · Proceedings of the National Academy of Sciences · 1988 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17