C R Buchanan

A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH‐binding activity by abolishing receptor homodimerization.

Philippe Duquesnoy, Marie‐Laure Sobrier, Bénédicte Duriez et al. · The EMBO Journal · 1994 · 156 citations · Full text

Life Sciences, Endocrinology, Genetics +17

Mortality, neoplasia, and Creutzfeldt-Jakob disease in patients treated with human pituitary growth hormone in the United Kingdom.

C R Buchanan, Michael A. Preece, R D Milner · BMJ · 1991 · 116 citations · Full text

Medicine, Endocrinology, Oncology +16

Changes in skeletal muscle and body composition after discontinuation of growth hormone treatment in growth hormone deficient young adults*

O. M. Rutherford, David A. Jones, J M Round et al. · Clinical Endocrinology · 1991 · 107 citations

Medicine, Endocrinology, Pediatrics +15

A monoclonal antibody to human insulin-like growth factor-I: characterization, use in radioimmunoassay and effect on the biological activities of the growth factor

David J. Morrell, H. Dadi, J More et al. · Journal of Molecular Endocrinology · 1989 · 62 citations

Life Sciences, Biochemistry, Endocrinology +15

Laron‐type dwarfism with apparently normal high affinity serum growth hormone‐binding protein

C R Buchanan, Hiralal Maheshwari, M. R. Norman et al. · Clinical Endocrinology · 1991 · 41 citations

Medicine, Endocrinology, Hormone Biochemistry +16