C R Buchanan

A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization.

Philippe Duquesnoy, Marie‐Laure Sobrier, Bénédicte Duriez et al. · The EMBO Journal · 1994 · 156 citations · Full text

Receptor Homodimerization, Signal Transduction, Growth Hormone +11

Mortality, neoplasia, and Creutzfeldt-Jakob disease in patients treated with human pituitary growth hormone in the United Kingdom.

C R Buchanan, Michael A. Preece, R D Milner · BMJ · 1991 · 116 citations · Full text

Changes in skeletal muscle and body composition after discontinuation of growth hormone treatment in growth hormone deficient young adults*

O. M. Rutherford, David A. Jones, J M Round et al. · Clinical Endocrinology · 1991 · 107 citations

A monoclonal antibody to human insulin-like growth factor-I: characterization, use in radioimmunoassay and effect on the biological activities of the growth factor

David J. Morrell, H. Dadi, J More et al. · Journal of Molecular Endocrinology · 1989 · 62 citations

Immunology, Pathology, Biological Activities +17

Laron‐type dwarfism with apparently normal high affinity serum growth hormone‐binding protein

C R Buchanan, Hiralal Maheshwari, M. R. Norman et al. · Clinical Endocrinology · 1991 · 41 citations