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Biasing the Parathyroid Hormone Receptor
24
Citations
52
References
2013
Year
Parathyroid Hormone ReceptorMedicinePhysiologyParathyroid HormoneParathyroid DiseaseParathyroid GlandEndocrinologyPharmacology
A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide
Harald Jüppner, Abdul‐Badi Abou‐Samra, Mason W. Freeman, +8
Science
G Protein-linked ReceptorMolecular BiologyParathyroid DiseasePeptide ScienceParathyroid Gland +17
1991
1.3K
Operational models of pharmacological agonism
J.W. Black, P. Leff
Proceedings of the Royal Society of London. Series B, Biological sciences
1983
1.1K
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.
Abdul‐Badi Abou‐Samra, Harald Jüppner, Thomas Force, +7
Proceedings of the National Academy of Sciences
SclerostinExpression CloningParathyroid GlandPthrp StimulationOsteoporosis +16
1992
1K
Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells.
Harald Dobnig, Russell T. Turner
Endocrinology
OsteogenesisParathyroid GlandOsteoporosisOrthopaedic SurgeryBone Lining Cells +16
1995
596
Effector Pathway-Dependent Relative Efficacy at Serotonin Type 2A and 2C Receptors: Evidence for Agonist-Directed Trafficking of Receptor Stimulus
Kelly A. Berg, Saul Maayani, Joseph Goldfarb, +3
Molecular Pharmacology
1998
512
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
Seungkirl Ahn, Sudha K. Shenoy, Huijun Wei, +1
Journal of Biological Chemistry
Differential KineticCellular PhysiologyMolecular PharmacologySignaling PathwayReceptor Tyrosine Kinase +15
2004
492
Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation
Diane Gesty‐Palmer, Minyong Chen, Éric Reiter, +8
Unique LigandsParathyroid GlandCellular PhysiologyMolecular PharmacologySignaling Pathway +17
2006
460
On the application of “a plausible model” of allosteric proteins to the receptor for acetylcholine
Arthur Karlin
Journal of Theoretical Biology
Molecular PharmacologyProteinlipid InteractionSignal TransductionBiochemistryG Protein-coupled Receptor +6
1967
428
Quantifying Ligand Bias at Seven-Transmembrane Receptors
Sudarshan Rajagopal, Seungkirl Ahn, David H. Rominger, +5
2011
387
Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
Janet M. Hock, István Gera
Journal of Bone and Mineral Research
366
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