Kathryn M. Appleton - Concepedia

Author

Kathryn M. Appleton

Medical University of South Carolina ORCID

Also Known As

Kathryn Appleton, Kathryn M Appleton, Kathryn M. Appleton

Publications

530

Citations

H-Index

Concepts

All Affiliations

Medical University of South Carolina Ralph H. Johnson VA Medical Center Michigan State University

About

Kathryn M. Appleton is an author at Medical University of South Carolina specializing in medicine, pharmacology, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	388
2	Cell Biology	2	2	247
3	Natural Sciences	1	1	219
4	Biochemistry	1	1	18
5	Biostatistics	1	1	12

Kathryn M. Appleton

Publications

502

Citations

H-Index

Page 1

	Year	Citations
The conformational signature of β-arrestin2 predicts its trafficking and signalling functions Mi‐Hye Lee, Kathryn M. Appleton, Erik G. Strungs, Nature Protein FunctionSignal TransductionConformational Signatureβ-Arrestin2 PredictsProtein Folding	2016	219
The Arrestin-selective Angiotensin AT1 Receptor Agonist [Sar1,Ile4,Ile8]-AngII Negatively Regulates Bradykinin B2 Receptor Signaling via AT1-B2 Receptor Heterodimers Parker C. Wilson, Mi‐Hye Lee, Kathryn M. Appleton, Journal of Biological Chemistry ImmunologyCellular PhysiologyInflammationMolecular PharmacologyKallikrein-kinin Systems	2013	49
S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization Mi‐Hye Lee, Kathryn M. Appleton, Hesham M. El‐Shewy, Journal of Lipid Research	2016	46
Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma Andrew J. Haak, Kathryn M. Appleton, Erika M. Lisabeth, Molecular Cancer Therapeutics	2016	45
Differential induction of CYP1A1 and CYP1B1 by benzo[a]pyrene in oral squamous cell carcinoma cell lines and by tobacco smoking in oral mucosa C. Angela, Kathryn M. Appleton, Joel B. Henriod, Oral Oncology Oral MucosaMedicinePharmacologyPathologyToxicology	2009	38
PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures Kathryn M. Appleton, Ashley Elrod, Katy A. Lassahn, Cancer Immunology Immunotherapy MedicinePathologyPd-1/pd-l1 Checkpoint InhibitorsImmune Checkpoint InhibitorTumor Targeting	2021	28
Biasing the Parathyroid Hormone Receptor Kathryn M. Appleton, Mi‐Hye Lee, Christian Alele, Methods in enzymology on CD-ROM/Methods in enzymology Parathyroid Hormone ReceptorMedicinePhysiologyParathyroid HormoneParathyroid Disease	2013	24
Development of inhibitors of heterotrimeric Gαi subunits Kathryn M. Appleton, Kevin J. Bigham, Christopher C. Lindsey, Bioorganic & Medicinal Chemistry Molecular PharmacologyBiochemistryG Protein-coupled ReceptorMedicineHeterotrimeric Gαi Subunits	2014	18
Emergent biological properties of arrestin pathway-selective biased agonism Kathryn M. Appleton, Louis M. Luttrell Journal of Receptors and Signal Transduction Signal TransductionReceptor ConformationG Protein-coupled ReceptorMedicineFunctional Selectivity	2013	12
A High-Content, Live-Cell, and Real-Time Approach to the Quantitation of Ligand-Induced β-Arrestin2 and Class A/Class B GPCR Mobilization Anthony Leonard, Kathryn M. Appleton, Louis M. Luttrell, Microscopy and Microanalysis	2013	12

Page 1