Demonstration of a two-step reaction mechanism for inhibition of alpha-thrombin by antithrombin III and identification of the step affected by heparin.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Enzyme structure and mechanism

D. T. Elmore · Endeavour · 1978 · 2.7K citations

Life Sciences, Biochemistry, Molecular Biology +13

Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor X<i>a</i> by spectrofluorimetric titration

G. W. Jameson, D. V. Roberts, Ralph W. Adams et al. · Biochemical Journal · 1973 · 375 citations · Full text

Life Sciences, Biochemistry, Chemistry +6

The kinetics of hemostatic enzyme-antithrombin interactions in the presence of low molecular weight heparin.

Robert E. Jordan, G.M. Oosta, W.T. Gardner et al. · Journal of Biological Chemistry · 1980 · 336 citations · Full text

Life Sciences, Biochemistry, Hematology +15

Studies on the Active Center of Trypsin

Marcos Mares-Guia, Elliott Shaw · Journal of Biological Chemistry · 1965 · 332 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +3