A Recombineering Pipeline to Make Conditional Targeting Constructs

One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products

Kirill A. Datsenko, Barry L. Wanner · Proceedings of the National Academy of Sciences · 2000 · 15.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

An efficient recombination system for chromosome engineering in <i>Escherichia coli</i>

Daiguan Yu, Hilary Ellis, E-Chiang Lee et al. · Proceedings of the National Academy of Sciences · 2000 · 1.7K citations

Life Sciences, Biotechnology, Genetics +16

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15

A new logic for DNA engineering using recombination in Escherichia coli

Youming Zhang, Frank Buchholz, Joep P. P. Muyrers et al. · Nature Genetics · 1998 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +16

New method for generating deletions and gene replacements in Escherichia coli

Carol M. Hamilton, Martí Aldea, B K Washburn et al. · Journal of Bacteriology · 1989 · 686 citations · Full text

Life Sciences, Biotechnology, Genetics +17