MDR1 Up-Regulated by Apoptotic Stimuli Suppresses Apoptotic Signaling

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

Drug Targeting, Glycosylation, Medicine +12

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

Monoclonal Antibody Mrk16, Cellular Localization, Immunology +18

Anti-cancer Drug Design

M SISSAOUI · Archives of Clinical Microbiology · 2018 · 1.4K citations

Drug Design, Medicine, Pharmacology +8

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

Full-length Cdna, Immunology, Molecular Biology +16

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

Preet M. Chaudhary, Igor B. Roninson · Cell · 1991 · 956 citations

Multidrug Efflux Pump, Medicine, Stem Cell Mobilization +11