Effects of serotonin on central neurons: microiontophoretic administration.

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

G. V. R. Born · Nature · 1962 · 4.3K citations

Medicine, Biochemistry, Hematology +14

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

Medicine, Cardiology, Hematology +13

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

Robert R. Gorman, S Bunting, O.V. Miller · Prostaglandins · 1977 · 655 citations

Medicine, Biochemistry, Pharmacology +10

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, Stuart Bunting et al. · Prostaglandins · 1976 · 605 citations

Life Sciences, Biochemistry, Physiology +16