Concepedia

Concordance of genetic and breath tests for lactose intolerance in a tertiary referral centre.

Marcin Krawczyk, Malgorzata Wolska, Stephanie Schwartz, Frank Gruenhage, Birgit Terjung, Piero Portincasa, Tilman Sauerbruch, Frank Lammert

PubMed · 2008 · 51 citations · 16 references

Abstract

In carriers of the CC-genotype, BTH and genotyping correlate perfectly, and the genetic test provides an unambiguous result. In BTH-positive individuals with a negative genetic test there is good reason to suspect secondary causes of lactase deficiency.

References

16

Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia

Mikko Kuokkanen · Gut · 2003 · 205 citations · Full text

BREATH HYDROGEN AS A DIAGNOSTIC METHOD FOR HYPOLACTASIA

Geoffrey Metz, T. B. Peters, DavidJ.A. Jenkins et al. · The Lancet · 1975 · 197 citations

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An upstream polymorphism associated with lactase persistence has increased enhancer activity

Jesper T. Troelsen, Jørgen Olsen, Jette Møller et al. · Gastroenterology · 2003 · 196 citations · Full text

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ISOLATED INTESTINAL LACTASE DEFICIENCY IN THE ADULT

Salvatore Auricchio, Max Landolt, A. Rubino et al. · The Lancet · 1963 · 189 citations

, , +5

Tolerance to small amounts of lactose in lactose maldigesters

TH Vesa, Timo Sahi · American Journal of Clinical Nutrition · 1996 · 121 citations

, , +4