Concepedia

CD40 expression in normal human cornea and regulation of CD40 in cultured human corneal epithelial and stromal cells.

Mitsuhiro Iwata, Koichi Soya, Mitsuru Sawa, T Sakimoto, David G. Hwang

PubMed · 2002 · 14 citations · 37 references

Abstract

In the human cornea, CD40 is expressed predominantly on limbal epithelial cells and also on cultured HCE cells with high proliferative potential. In addition, the expression of CD40 is induced on cultured HCE and HCS cells differentially by proinflammatory cytokines, such as IFN-gamma and TNF-alpha.

References

37

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

Marina Cella, Doris Scheidegger, Kathrin Palmer-Lehmann et al. · The Journal of Experimental Medicine · 1996 · 2K citations · Full text

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

Roberto Manetti, Paola Parronchi, M G Giudizi et al. · The Journal of Experimental Medicine · 1993 · 1.7K citations · Full text

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Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.

Alexander Schermer, Sharon Galvin, Tung‐Tien Sun · The Journal of Cell Biology · 1986 · 1.4K citations · Full text

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Activation of human dendritic cells through CD40 cross-linking.

Christophe Caux, Catherine Massacrier, Béatrice Vanbervliet et al. · The Journal of Experimental Medicine · 1994 · 1.3K citations · Full text

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The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

Christian Grønhøj, Arthur O. Anderson, Ettore Appella et al. · Science · 1989 · 1K citations

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