Interleukin‐1 beta converting enzyme requires oligomerization for activity of processed forms in vivo.

Rapid and efficient site-specific mutagenesis without phenotypic selection.

Thomas A. Kunkel · Proceedings of the National Academy of Sciences · 1985 · 7.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

Life Sciences, Immunology, Molecular Biology +12

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Cell · 1993 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

Masahiko Miura · Cell · 1993 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +13

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

Yutaka Takebe, Motoharu Seiki, Jun–ichi Fujisawa et al. · Molecular and Cellular Biology · 1988 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17