Probing protein-protein interactions in real time.

Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

Matthias Rief, Mathias Gautel, Filipp Oesterhelt et al. · Science · 1997 · 3K citations

Engineering, Antigen Processing, Cytoskeleton +17

Single-Molecule Enzymatic Dynamics

H. Peter Lu · 1998 · 1.5K citations

Single Molecule Biophysics, Single-molecule Enzymatic Dynamics, Biochemistry +11

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

K. Braig, Zbyszek Otwinowski, Rashmi S. Hegde et al. · Nature · 1994 · 1.3K citations

Crystal Structure, Biochemistry, Natural Sciences +7

The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex

Zhaohui Xu, Arthur L. Horwich, Paul B. Sigler · Nature · 1997 · 1.3K citations

Crystal Structure, Molecular Biology, Molecular Complex +2

Tapping mode atomic force microscopy in liquids

Paul K. Hansma, J. P. Cleveland, Manfred Radmacher et al. · Applied Physics Letters · 1994 · 864 citations

Tapping Frequency, Contact Mode, Engineering +14