RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Charity W. Law, Yunshun Chen, Wei Shi et al. · Genome biology · 2014 · 6.7K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +12

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

Yaming Wang, Marina Cella, Kaitlin Mallinson et al. · Cell · 2015 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Bin Zhang, Chris Gaiteri, Liviu‐Gabriel Bodea et al. · Cell · 2013 · 1.8K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

The microglial sensome revealed by direct RNA sequencing

Suzanne E. Hickman, Nathan D. Kingery, Toshiro K. Ohsumi et al. · Nature Neuroscience · 2013 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14