Concepedia

Simultaneous determination of febuxostat and its three active metabolites in human plasma by liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study in Chinese healthy volunteers

Yingli Wu, Zhengsheng Mao, You‐Ping Liu, Xin Wang, Xin Di

Journal of Pharmaceutical and Biomedical Analysis · 2015 · 27 citations · 10 references

DOI

Concepts

References

10

Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout

Michael A. Becker, H. Ralph Schumacher, Robert L. Wortmann et al. · New England Journal of Medicine · 2005 · 1.3K citations · Full text

Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study

H. Ralph Schumacher, Michael A. Becker, Elisabeth A. Lloyd et al. · Lara D. Veeken · 2008 · 249 citations

Pharmacokinetics and Pharmacodynamics of Febuxostat, a New Non-purine Selective Inhibitor of Xanthine Oxidase in Subjects with Renal Impairment

Michael D. Mayer, Reza Khosravan, Laurent Vernillet et al. · American Journal of Therapeutics · 2005 · 153 citations

Pharmacokinetics, Pharmacodynamics and Safety of Febuxostat, a Non-Purine Selective Inhibitor of Xanthine Oxidase, in a Dose Escalation Study in Healthy Subjects

Reza Khosravan, Brian Grabowski, Jingtao Wu et al. · Clinical Pharmacokinetics · 2006 · 104 citations

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Effect of food or antacid on pharmacokinetics and pharmacodynamics of febuxostat in healthy subjects

Reza Khosravan, Brian Grabowski, Jingtao Wu et al. · British Journal of Clinical Pharmacology · 2007 · 81 citations · Full text