Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout

Abstract

Febuxostat, at a daily dose of 80 mg or 120 mg, was more effective than allopurinol at the commonly used fixed daily dose of 300 mg in lowering serum urate. Similar reductions in gout flares and tophus area occurred in all treatment groups.