Concepedia

NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD

Yoichi Kakuta, Takeo Naito, M. Onodera, Masatake Kuroha, T. Kimura, Hisashi Shiga, Katsuya Endo, Kenichi Negoro, Yoshitaka Kinouchi, Tooru Shimosegawa

The Pharmacogenomics Journal · 2015 · 163 citations · 22 references

DOI

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References

22

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

Jean‐Frédéric Colombel, William J. Sandborn, Walter Reinisch et al. · New England Journal of Medicine · 2010 · 3.1K citations · Full text

, , +14

Phototyping: comprehensive DNA typing for HLA‐A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence‐specific primers (PCR‐SSP)

Michael Bunce, C. M. O'Neill, Martin Barnardo et al. · Tissue Antigens · 1995 · 1K citations

, , +17

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

Alan G. Fraser · Gut · 2002 · 630 citations · Full text

, , +13

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

Jean‐Frédéric Colombel, Nicolas Ferrari, Hervé Debuysère et al. · Gastroenterology · 2000 · 615 citations · Full text

, , +17

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

Suk‐Kyun Yang, Myunghee Hong, Jiwon Baek et al. · Nature Genetics · 2014 · 547 citations · Full text

, , +7