Hisashi Shiga

NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD

Yoichi Kakuta, Takeo Naito, M. Onodera et al. · The Pharmacogenomics Journal · 2015 · 163 citations

Medicine, Dermatology, Hematology +7

NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study

Yoichi Kakuta, Yosuke Kawai, Daisuke Okamoto et al. · Journal of Gastroenterology · 2018 · 124 citations · Full text

Life Sciences, Genetics, Pharmacology +17

Changes of faecal microbiota in patients with Crohn's disease treated with an elemental diet and total parenteral nutrition

Hisashi Shiga, Takayuki Kajiura, Junko Shinozaki et al. · Digestive and Liver Disease · 2012 · 76 citations

Agriculture, Microbiology, Nutrition +16

MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6

Toshihiro Tadano, Yoichi Kakuta, Shin Hamada et al. · World Journal of Gastrointestinal Oncology · 2016 · 76 citations · Full text

Medicine, Molecular Biology, Oncology +17

FCGR3A-158 polymorphism influences the biological response to infliximab in Crohn’s disease through affecting the ADCC activity

Rintaro Moroi, Katsuya Endo, Yoshitaka Kinouchi et al. · Immunogenetics · 2013 · 75 citations

Life Sciences, Genetics, Immunology +16