Concepedia

Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors

Lotke Tambuyzer, Hilde Azijn, L Rimsky, Johan Vingerhoets, Pierre Lecocq, Guenter Kraus, Gastón Picchio, Marie‐Pierre de Béthune

Antiviral Therapy · 2009 · 93 citations · 39 references

DOIFull text

Open access

Abstract

The list of 44 NNRTI RAMs compiled in this study provides a comprehensive overview of mutations that play a role in HIV-1 NNRTI resistance and can be used to guide further in vitro and in vivo research on the mechanisms of HIV-1 NNRTI resistance.

References

39

Antiretroviral-Drug Resistance among Patients Recently Infected with HIV

Susan J. Little, Sarah Holte, Jean‐Pierre Routy et al. · New England Journal of Medicine · 2002 · 1.1K citations · Full text

46th Interscience Conference on Antimicrobial Agents and Chemotherapy

Jordi Vilà, Robert A. Bonomo · Future Microbiology · 2007 · 420 citations

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Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

Jack H. Nunberg, William A. Schleif, Evelyn Boots et al. · Journal of Virology · 1991 · 363 citations · Full text

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TMC125, a Novel Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor Active against Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Human Immunodeficiency Virus Type 1

Koen Andries, Hilde Azijn, Theo Thielemans et al. · Antimicrobial Agents and Chemotherapy · 2004 · 322 citations · Full text

, , +17

Human Immunodeficiency Virus Type 1 Mutations Selected in Patients Failing Efavirenz Combination Therapy

Lee T. Bacheler, Elizabeth D. Anton, Phil Kudish et al. · Antimicrobial Agents and Chemotherapy · 2000 · 270 citations · Full text

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