Improving Stability and Release Kinetics of Microencapsulated Tetanus Toxoid by Co-Encapsulation of Additives

Biodegradable microspheres as controlled-release tetanus toxoid delivery systems

Marı́a José Alonso, Caroline J. Min, George R. Siber et al. · Vaccine · 1994 · 313 citations

Pharmacy, Bioengineering, Pharmaceutics +14

Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly (d,l-lactic acid-co-glycolic acid) microspheres

Tae Gwan Park, Weiqi Lu, George Crotts · Journal of Controlled Release · 1995 · 256 citations

Pharmacy, Biochemistry, Pharmaceutics +16

Determinants of Release Rate of Tetanus Vaccine from Polyester Microspheres

Marı́a José Alonso, Smadar Cohen, Tae G. Park et al. · Pharmaceutical Research · 1993 · 222 citations

Veterinary Medicine, Immunology, Pharmaceutics +16

Tetanus toxoid and synthetic malaria antigen containing poly(lactide)/poly(lactide-co-glycolide) microspheres: importance of polymer degradation and antigen release for immune response

Claudio Thomasin, Giampietro Corradin, Ying Men et al. · Journal of Controlled Release · 1996 · 188 citations

Veterinary Medicine, Biotechnology, Immunology +17

Microencapsulation of rh-erythropoietin, using biodegradable poly(d,l-lactide-co-glycolide): protein stability and the effects of stabilizing excipients

Michael M. Morlock, Hans Koll, Gerhard Winter et al. · European Journal of Pharmaceutics and Biopharmaceutics · 1997 · 187 citations

Pharmacy, Biotechnology, Molecular Pharmaceutics +14