TLR4 Mediates Pneumolysin-Induced ATF3 Expression through the JNK/p38 Pathway in Streptococcus pneumoniae-Infected RAW 264.7 Cells

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4

Mark Gilchrist, Vésteinn Thórsson, Bin Li et al. · Nature · 2006 · 794 citations

Inflammation, Toll-like Receptors, Molecular Immunology +15

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

Richard Malley, Philipp Henneke, Sarah C. Morse et al. · Proceedings of the National Academy of Sciences · 2003 · 699 citations · Full text

ATF3 and stress responses.

T Hai, Curt D. Wolfgang, D K Marsee et al. · PubMed · 1999 · 643 citations · Full text

Genetics, Cell Death, Social Sciences +19

Lipoteichoic Acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus Activates Immune Cells via Toll-like Receptor (TLR)-2, Lipopolysaccharide-binding Protein (LBP), and CD14, whereas TLR-4 and MD-2 Are Not Involved

Nicolas W.J. Schröder, Siegfried Morath, Christian Alexander et al. · Journal of Biological Chemistry · 2003 · 630 citations · Full text

c-Jun Can Recruit JNK to Phosphorylate Dimerization Partners via Specific Docking Interactions

Tuula Kallunki, Tiliang Deng, Masahiko Hibi et al. · Cell · 1996 · 493 citations · Full text

Signal Transduction, Medicine, Natural Sciences +11