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Classically activated macrophages undergo functionally significant nucleotide metabolism remodelling driven by nitric oxide

Steven V John, Gretchen Seim, Billy J Erazo-Flores, James A. Votava, Uzziah Urquiza, Nicholas L. Arp, John Steill, Jack Freeman, Lauren N. Carnevale, Xin Qing,

Nature Metabolism · 2025 · 22 citations · 48 references

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48

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira, Jeffrey A. Haspel, Vijay Rathinam et al. · Nature Immunology · 2010 · 3K citations · Full text

, , +15

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

Jianguo Xia, Nikolaos Psychogios, N. Young et al. · Nucleic Acids Research · 2009 · 2.3K citations · Full text

, , +17

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada, Timothy R. Crother, Justin N. Karlin et al. · Immunity · 2012 · 2.2K citations · Full text

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Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

Abhishek Jha, Stanley Ching‐Cheng Huang, Alexey Sergushichev et al. · Immunity · 2015 · 2K citations · Full text

, , +17