Concepedia

FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression

Christy Gliniak, Ruth Gordillo, Yun‐Hee Youm, Qian Lin, Clair Crewe, Zhuzhen Zhang, Bianca C. Field, Teppei Fujikawa, Megan Virostek, Shangang Zhao,

Cell Metabolism · 2025 · 36 citations · 72 references

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72

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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Obesity is associated with macrophage accumulation in adipose tissue

Stuart P. Weisberg, Daniel McCann, Manisha Desai et al. · Journal of Clinical Investigation · 2003 · 8.3K citations · Full text

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Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.5K citations

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Carey N. Lumeng, Jennifer L. Bodzin, Alan R. Saltiel · Journal of Clinical Investigation · 2007 · 4.6K citations · Full text

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Bolormaa Vandanmagsar, Yun‐Hee Youm, Anthony Ravussin et al. · Nature Medicine · 2011 · 2.6K citations · Full text

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