Concepedia

Targeting the BCKDK/BCLAF1/MYC/HK2 axis to alter aerobic glycolysis and overcome Trametinib resistance in lung cancer

Jiajia Yang, Zixia Yang, Ran Liu, Jing Jia, Xinrui Zhang, Yuting Zhang, Zhi Yao, Junqiang Lv

Cell Death and Differentiation · 2025 · 11 citations · 41 references

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References

41

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. · CA A Cancer Journal for Clinicians · 2018 · 87.7K citations · Full text

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Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Mathieu Laversanne, Hyuna Sung et al. · CA A Cancer Journal for Clinicians · 2024 · 23.1K citations · Full text

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Next-generation characterization of the Cancer Cell Line Encyclopedia

Mahmoud Ghandi, Franklin W. Huang, Judit Jané‐Valbuena et al. · Nature · 2019 · 3.7K citations · Full text

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Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1

Jung‐whan Kim, Ping Gao, Yen-Chun Liu et al. · Molecular and Cellular Biology · 2007 · 641 citations · Full text

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NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

Hengxing Chen, Yun Li, Huafu Li et al. · Nature · 2024 · 485 citations · Full text

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