Concepedia

Iodine deficiency up-regulates monocarboxylate transporter 8 expression of mouse thyroid gland

Zhimei Hu, Xiaohua Zhuo, Yanan Shi, Xin Liu, Jihong Yuan, Lanying Li, Yina Sun

Chinese Medical Journal · 2014 · 11 citations · 13 references

DOIFull text

Open access

Abstract

There is a compensatory increase in thyroid MCT8 expression to enhance its capability to transport TH from thyroid to the blood circulation in iodine deficient mice.

References

13

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter

Edith C. H. Friesema, Sumita Ganguly, A. E. D. Abdalla et al. · Journal of Biological Chemistry · 2003 · 711 citations · Full text

A Novel Syndrome Combining Thyroid and Neurological Abnormalities Is Associated with Mutations in a Monocarboxylate Transporter Gene

Alexandra M. Dumitrescu, Xiao-Hui Liao, Thomas B. Best et al. · The American Journal of Human Genetics · 2004 · 699 citations · Full text

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Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

Edith C. H. Friesema, Annette Grueters, Heike Biebermann et al. · The Lancet · 2004 · 697 citations · Full text

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Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past

T. Nigel PRICE, Nikki Jackson, Andrew P. Halestrap · Biochemical Journal · 1998 · 357 citations · Full text

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