Indole lactic acid derived from Akkermansia muciniphila activates the aryl hydrocarbon receptor to inhibit ferroptosis in ischemic stroke

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

Medicine, Neuroscience, Surgery +17

A Semiautomated Method for Measuring Brain Infarct Volume

Raymond A. Swanson, Matthew T. Morton, George Tsao-Wu et al. · Journal of Cerebral Blood Flow & Metabolism · 1990 · 1.7K citations

Medicine, Neurology, Neuroscience +16

Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity

Qingqing Zhang, Qing Zhao, Tao Li et al. · Cell Metabolism · 2023 · 415 citations · Full text

Life Sciences, Immunology, Oncology +17

Rapid gut dysbiosis induced by stroke exacerbates brain infarction in turn

Kaiyu Xu, Xuxuan Gao, Genghong Xia et al. · Gut · 2021 · 289 citations

Life Sciences, Microbiology, Nutritional Sciences +17

Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

Bashar Shuoker, Michael Jakob Pichler, Chunsheng Jin et al. · Nature Communications · 2023 · 163 citations · Full text

Life Sciences, Biochemistry, Microbiology +16