Concepedia

Inhibition of Drp1-mediated mitochondrial fission by P110 ameliorates renal injury in diabetic nephropathy

Ruchi Yue, Ziyu Yan, Hongchu Zha, Yao Xia, Hua Huang, Huimin Li, Mao Ding, Marwan Ibrahim Abdullah, Lang Shi, Jiefu Zhu,

International Immunopharmacology · 2025 · 12 citations · 27 references

DOI

Concepts

References

27

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Erin Quan Toyama, Sébastien Herzig, Julien Courchet et al. · Science · 2016 · 1.1K citations · Full text

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Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

Craig R. Brooks, Qingqing Wei, Sung-Gyu Cho et al. · Journal of Clinical Investigation · 2009 · 737 citations · Full text

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Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

Weier Qi, Hillary A. Keenan, Qian Li et al. · Nature Medicine · 2017 · 493 citations

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Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial Cells

Wenjian Wang, Yin Wang, Jianyin Long et al. · Cell Metabolism · 2012 · 471 citations · Full text

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Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration

Xing Guo, Marie‐Hélène Disatnik, Marie Monbureau et al. · Journal of Clinical Investigation · 2013 · 383 citations

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