Concepedia

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

Weier Qi, Hillary A. Keenan, Qian Li, Atsushi Ishikado, Aimo Kannt, Thorsten Sadowski, Mark A. Yorek, I‐Hsien Wu, Sam Lockhart, Lawrence J. Coppey,

Nature Medicine · 2017 · 493 citations · 53 references

DOI

Concepts

References

53

The Pathobiology of Diabetic Complications

Michael Brownlee · Diabetes · 2005 · 5.3K citations · Full text

, , +12

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Takeshi Nishikawa, Diane Edelstein, Xue Du et al. · Nature · 2000 · 4.3K citations

, , +14

Pathologic Classification of Diabetic Nephropathy

Thijs W. Cohen Tervaert, Antien L. Mooyaart, Kerstin Amann et al. · Journal of the American Society of Nephrology · 2010 · 1.7K citations

, , +17

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

Hyun Mi Kang, Seon Ho Ahn, Peter S. Choi et al. · Nature Medicine · 2014 · 1.5K citations · Full text

, , +16

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

Weibo Luo, Hongxia Hu, Ryan Chang et al. · Cell · 2011 · 1.4K citations · Full text

, , +16