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BMC Medicine · 2025 · 11 citations · 41 references
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Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
Jack Bowden, George Davey Smith, Stephen Burgess · International Journal of Epidemiology · 2015 · 10.2K citations · Full text
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
Jack Bowden, George Davey Smith, Philip Haycock et al. · Genetic Epidemiology · 2016 · 9.2K citations · Full text
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
Marie Verbanck, Chia‐Yen Chen, Benjamin M. Neale et al. · Nature Genetics · 2018 · 8.8K citations · Full text
Linkage Disequilibrium, Epidemiology, Genotype-phenotype Association +13
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.4K citations
Interpreting findings from Mendelian randomization using the MR-Egger method
Stephen Burgess, Simon G. Thompson · European Journal of Epidemiology · 2017 · 4.6K citations · Full text