Nature Communications · 2025 · 41 citations · 50 references
EngineeringManufacturing EngineeringMaterials EngineeringAdditive ManufacturingDigital ImagingMicrofabrication3D Bioprinting3D PrintingBioprintingHolographyOptical PrintingCell-laden HydrogelsLight ProjectionPhase ModulationPhotocurable ResinsPrinting TechnologiesSpeckle Noise ReductionSpeckle PhenomenaVolumetric Additive Manufacturing
Several 3D light-based printing technologies have been developed that rely on the photopolymerization of liquid resins. A recent method, so-called Tomographic Volumetric Additive Manufacturing, allows the fabrication of microscale objects within tens of seconds without the need for support structures. This method works by projecting intensity patterns, computed via a reverse tomography algorithm, into a photocurable resin from different angles to produce a desired 3D shape when the resin reaches the polymerization threshold. Printing using incoherent light patterning has been previously demonstrated. In this work, we show that a light engine with holographic phase modulation unlocks new potential for volumetric printing. The light projection efficiency is improved by at least a factor 20 over amplitude coding with diffraction-limited resolution and its flexibility allows precise light control across the entire printing volume. We show that computer-generated holograms implemented with tiled holograms and point-spread-function shaping mitigates the speckle noise which enables the fabrication of millimetric 3D objects exhibiting negative features of 31 μm in less than a minute with a 40 mW light source in acrylates and scattering materials, such as soft cell-laden hydrogels, with a concentration of 0.5 million cells per mL.
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