clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han, +1

OMICS A Journal of Integrative Biology

GeneticsGenomicsGene RecognitionBioinformatics DatabaseR Package +22

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert, +2

Nature Biotechnology

EngineeringGeneticsMultiomicsSingle-cell Transcriptomic DataTranscriptomics Technology +15

clusterProfiler 4.0: A universal enrichment tool for interpreting omics data

Tianzhi Wu, Erqiang Hu, Shuangbin Xu, +11

The Innovation

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby, +7

Nature Biotechnology

Pattern FormationDevelopmental BiologyCell DivisionCell InteractionSingle-cell Biology +10

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing

Chunhong Zheng, Liangtao Zheng, Jae‐Kwang Yoo, +13

Cell

HepatologyHealth SciencesTumor HeterogeneityMedicineLiver Physiology +12

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

Enli Liu, David Marín, Pinaki P. Banerjee, +24

New England Journal of Medicine

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Brian C. Miller, Debattama R. Sen, Rose Al Abosy, +24

Nature Immunology

Mediate Tumor ControlCancer ImmunosurveillanceImmunologyTumor ImmunityImmune Checkpoint Inhibitor +6

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

Antonio Di Stasi, Siok‐Keen Tey, Gianpietro Dotti, +16

New England Journal of Medicine

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

Margherita Norelli, Barbara Camisa, Giulia Barbiera, +14

Nature Medicine

InflammationCar T CellsCytokineAutoimmune DiseaseMonocyte-derived Il-1 +10

Pan-cancer single-cell landscape of tumor-infiltrating T cells

Liangtao Zheng, Shishang Qin, Wen Si, +16

Science