Concepedia

HFIP-promoted formal [2π + 2σ] cycloaddition of <i>para</i>-quinone methides with bicyclo[1.1.0]butanes: an approach towards spiro-bicyclo[2.1.1]hexanes

Haijian Wu, Manman Sun, Jing Zhang, Zhiming Wang, Jianguo Yang, Gangguo Zhu

Organic Chemistry Frontiers · 2025 · 25 citations · 50 references

DOI

Concepts

Abstract

A formal [2π + 2σ] cycloaddition of BCBs with p -QMs has been developed using HFIP (2 M) as the solvent without an additional catalyst to enable the rapid construction of spiro-BCHs.

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