Concepedia

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection

Arun R. K. Kumar, Jessalyn Low, Jet Lim, Ba Myint, Xinhong Sun, Ling Wu, Hong Sheng Cheng, Sophronia Yip, Cyrus Zai Ming Cheng, Thamizhanban Manoharan,

Biomaterials · 2025 · 16 citations · 28 references

Concepts

Life SciencesBiotechnologyImmunologyGene DeliveryGenetic EngineeringNanobiotechnologyGene Delivery To Immune CellsGenetic Engineering Of CellsImmune Cell EngineeringNanomedicineNanoparticle-based ImmunotechnologyImmune Cell Gene TransferNonviral Gene Delivery To Immune CellsPrimary CellsTargeted TransfectionTransfection ReagentsViral Vector Delivery To Immune Cells

References

28

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 112.5K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Shannon L. Maude, Noelle V. Frey, Pamela A. Shaw et al. · New England Journal of Medicine · 2014 · 5.4K citations · Full text

Life Sciences, Hematology, Immunology +17

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

Stephan A. Grupp, Michael Kalos, David M. Barrett et al. · New England Journal of Medicine · 2013 · 3.5K citations · Full text

Life Sciences, Hematology, Immunology +16

CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

Cameron J. Turtle, Laïla‐Aïcha Hanafi, Carolina Berger et al. · Journal of Clinical Investigation · 2016 · 2.1K citations · Full text

Medicine, Immunology, Oncology +17

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

Salima Hacein‐Bey‐Abina, Alexandrine Garrigue, Gary P. Wang et al. · Journal of Clinical Investigation · 2008 · 1.8K citations · Full text

Medicine, Molecular Genetics, Oncology +14