SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage - Concepedia

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SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage

DOI Full Paper Access

10

Citations

18

References

2024

Year

Jia-Qing Sun, Bin Sheng, Sen Gao, Xun-Zhi Liu, Yue Cui, Zheng Peng, Xiang-Xin Chen, Peng-Fei Ding, Zong Zhuang, Lingyun Wu,

Journal of Inflammation Research

Abstract

In summary, SIRT2 promoted microglial pyroptosis, primarily by increasing the expression and activity of Foxo3a, thereby exacerbating neuroinflammatory damage following subarachnoid hemorrhage.

References

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