Concepedia

Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy

Shuang Li, Jianchao Zhang, Wanrong Fu, Jinhua Cao, Zhonggen Li, Xiaoxu Tian, Meng Yang, Jing Zhao, Chuchu Wang, Yangyang Liu,

Cell Reports · 2024 · 12 citations · 23 references

DOIFull text

Open access

Concepts

Abstract

homeostasis imbalance in SLC25A3-KO hiPSC-CMs. Finally, we explored the prospective therapeutic implications of mitochondrial transplantation in rescuing SLC25A3-related HCM.

References

23

NF-κB signaling in inflammation

Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy · 2017 · 8.1K citations · Full text

, , +17

Chemically defined generation of human cardiomyocytes

Paul W. Burridge, Elena Matsa, Praveen Shukla et al. · Nature Methods · 2014 · 1.6K citations · Full text

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Cardiac Energy Metabolism in Heart Failure

Circulation Research · 2021 · 1.3K citations · Full text

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Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy

Circulation · 2021 · 295 citations · Full text

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Molecular Genetic Basis of Hypertrophic Cardiomyopathy

Circulation Research · 2021 · 230 citations · Full text

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