Mitochondrial Therapy

Mitochondrial therapy is a research field and therapeutic approach focused on investigating the role of mitochondrial dysfunction in disease pathogenesis and developing strategies to restore mitochondrial health. This field seeks to address a diverse range of conditions associated with impaired cellular energy production and increased oxidative stress by targeting these critical organelles.

515

Publications

32.5K

Citations

3.1K

Authors

970

Institutions

Publications per year

2017–2026

139

Parents

Mitochondrial Medicine

Publications

515

Leigh syndrome: Clinical features and biochemical and DNA abnormalities

S. Rahman, Rozanne B. Blok, H H Dahl et al. · Annals of Neurology · 1996 · 776 citations

Down Syndrome, Complex Iv-deficient Sibships, Genetic Testing +13

A double‐blind, placebo‐controlled study to assess the mitochondria‐targeted antioxidant MitoQ as a disease‐modifying therapy in Parkinson's disease

Barry Snow, Fiona L. Rolfe, Michelle Lockhart et al. · Movement Disorders · 2010 · 588 citations

Mitochondrial Oxidative Stress, Neurodegenerative Diseases, Mitochondrial Function +15

Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.

John M. Shoffner, Marie T. Lott, Alexander S. Voljavec et al. · Proceedings of the National Academy of Sciences · 1989 · 503 citations · Full text

Ocular Disease, Genetics, Molecular Biology +23

A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations

Weiwei Fan, Katrina G. Waymire, Navneet Narula et al. · Science · 2008 · 469 citations · Full text

Biology, Mitochondrial Myopathy, Genome Instability +13

Mitochondrial Respiratory Chain Supercomplexes Are Destabilized in Barth Syndrome Patients

Matthew McKenzie, Michael Lazarou, David R. Thorburn et al. · Journal of Molecular Biology · 2006 · 423 citations

Mendelian Disorder, Mitochondrial Function, Mitochondrial Dynamic +8

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Authors

3.1K

Leading researchers in Mitochondrial Therapy. Counts cover only their work on this concept, not their overall record.

	Publications	Citations	H-Index
DM Douglass M. Turnbull Newcastle University	15	1.3K	13
RW Robert W. Taylor Newcastle University	15	763	13
PF Patrick F. Chinnery Newcastle University	12	1.3K	11
RJ Richard J. Rodenburg Radboud University Nijmegen	10	441	10
RM Robert McFarland Newcastle University	10	704	10

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Institutions

970

Leading universities and research organizations in Mitochondrial Therapy. Counts cover only their work on this concept, not their overall record.

	Publications	Citations	H-Index
Newcastle University Newcastle upon Tyne, United Kingdom	133	13.1K	22
Wellcome Centre for Mitochondrial Research Newcastle upon Tyne, United Kingdom	95	6.2K	17
Radboud University Nijmegen Nijmegen, The Netherlands	77	4K	15
Inserm Paris, France	71	4.5K	15
University College London London, United Kingdom	57	2.1K	14

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Venues

Leading journals and conferences in Mitochondrial Therapy. Counts cover only their publications on this concept, not their overall record.

	Publications	Citations	H-Index
Human Molecular Genetics	19	1K	18
PubMed	27	1.3K	18
Mitochondrion	23	682	17
Neurology	13	994	12
Molecular Genetics and Metabolism	11	728	11

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