<i>APOL1</i> Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans

Abstract

In this study, monoallelic <i>APOL1</i> variants were associated with 18% higher odds of CKD and 61% higher odds of focal segmental glomerulosclerosis; biallelic <i>APOL1</i> variants were associated with 25% higher odds of CKD and 84% higher odds of focal segmental glomerulosclerosis. (Funded by the National Human Genome Research Institute and others.).