Proteogenomic Identification and Analysis of KIF5B as a PrognosticSignature for Hepatocellular Carcinoma

Abstract

Our findings have suggested KIF5B protein to function as a novel prognostic biomarker in HCC. KIF5B expression has been found to activate the AKT/mTOR pathway and reprogram triglyceride metabolism, leading to HCC development. Targeting KIF5B may be an effective strategy in the clinical treatment of HCC.