Serine and glycine physiology reversibly modulate retinal and peripheral nerve function

Tissue-based map of the human proteome

Mathias Uhlén, Linn Fagerberg, Björn M. Hallström et al. · Science · 2015 · 15.3K citations · Full text

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell · 2015 · 7.6K citations · Full text

Systems Biology, Functional Genomics, Single Cell Sequencing +12

A general framework for estimating the relative pathogenicity of human genetic variants

Martin Kircher, Daniela Witten, Preti Jain et al. · Nature Genetics · 2014 · 6.4K citations · Full text

Relative Pathogenicity, Genetics, Genetic Epidemiology +16

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

Linn Fagerberg, Björn M. Hallström, Per Oksvold et al. · Molecular & Cellular Proteomics · 2013 · 3.7K citations · Full text

Engineering, Immunology, Pathology +26

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Nilah M. Ioannidis, Joseph H. Rothstein, Vikas Pejaver et al. · The American Journal of Human Genetics · 2016 · 2.8K citations · Full text

Genome-wide Association Study, Allelic Variant, Genotype-phenotype Association +14