CRISPR-repressed toxin–antitoxin provides herd immunity against anti-CRISPR elements

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

Ekaterina Semenova, Matthijs M. Jore, Kirill A. Datsenko et al. · Proceedings of the National Academy of Sciences · 2011 · 781 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

Blake Wiedenheft, Esther van Duijn, Jelle B. Bultema et al. · Proceedings of the National Academy of Sciences · 2011 · 463 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

Joseph Bondy‐Denomy, Bianca Garcı́a, Scott Strum et al. · Nature · 2015 · 377 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer

Corinna Richter, Ron L. Dy, Rebecca E. McKenzie et al. · Nucleic Acids Research · 2014 · 191 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors

Lakshminarayan M. Iyer, Eugene V. Koonin, L. Aravind · Genome biology · 2002 · 138 citations · Full text

Life Sciences, Biology, Molecular Biology +17