Ekaterina Semenova

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

Omar O. Abudayyeh, Jonathan S. Gootenberg, Silvana Konermann et al. · Science · 2016 · 2.3K citations · Full text

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

Sergey Shmakov, Omar O. Abudayyeh, Kira S. Makarova et al. · Molecular Cell · 2015 · 1.2K citations · Full text

Off-target Effect, Functional Genomics, Engineering +11

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

Ekaterina Semenova, Matthijs M. Jore, Kirill A. Datsenko et al. · Proceedings of the National Academy of Sciences · 2011 · 773 citations · Full text

Short Palindromic Repeat, Engineering, Genetics +15

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

Kirill A. Datsenko, Ksenia Pougach, Anton Tikhonov et al. · Nature Communications · 2012 · 580 citations · Full text

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

Edze R. Westra, Paul B. G. van Erp, Tim Künne et al. · Molecular Cell · 2012 · 528 citations · Full text

Consecutive Binding, Natural Sciences, Crispr Immunity Relies +10