Initial Management of <i>BRAF </i>V600E-Variant Anaplastic Thyroid Cancer

Sarah Hamidi, Ramona Dadu, Mark Zafereo, Renata Ferrarotto, Jennifer Wang, Anastasios Maniakas, G. Brandon Gunn, Anna Lee, Michael T. Spiotto, Priyanka Iyer,

JAMA Oncology · 2024 · 28 citations · 32 references

Abstract

This Consensus Statement from the FAST (Facilitating Anaplastic Thyroid Cancer Specialized Treatment) group at MD Anderson Cancer Center emphasizes that rapid identification of a BRAF V600E pathogenic variant and timely initiation of sequential therapy are critical to avoid excess morbidity and mortality in patients with BRAFv-ATC. In the past decade, remarkable progress has been made in the treatment of patients with BRAFv-ATC, justifying these new evidence-based recommendations reached through a consensus of experts from a high-volume center.

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